Preheat your oven to 425°F (220°C) and line a baking sheet with parchment paper or a wire rack. Separate the onion slices into rings and set aside. Place the flour in a shallow bowl. In another bowl, whisk together the eggs and milk. In a third bowl, combine the panko breadcrumbs, paprika, garlic powder, salt, and pepper. Dredge each onion ring in the flour, shaking off excess, then dip into the egg mixture, and coat thoroughly in the breadcrumb mixture. Place the coated rings on the prepared baking sheet, ensuring they don’t overlap. Lightly spray the onion rings with cooking spray to help them crisp up. Bake for 15-20 minutes, flipping halfway through, until golden and crispy. Serve immediately with your favorite dipping sauce.