There’s something wonderfully comforting about a rich, creamy casserole that can warm your heart and fill your stomach. The velvety texture and savory flavor of Creamy Chicken and Turkey Slice Casserole make it an irresistible dish for family gatherings, cozy nights, or even a simple weeknight dinner. This recipe is particularly special because it combines the richness of two beloved proteins—chicken and turkey—into one creamy indulgence. Did you know casseroles have been a staple in American kitchens for decades? They’re the perfect blend of simplicity and flavor, and this one is no exception!
What makes this dish even more appealing is its ease of preparation compared to other popular recipes, like lasagna or shepherd’s pie. With just a few ingredients and simple steps, you can create a dish that will have your family asking for seconds. So, gather your loved ones and prepare to indulge in a hug-in-a-bowl kind of meal!
What is Creamy Chicken and Turkey Slice Casserole?
So, what exactly is Creamy Chicken and Turkey Slice Casserole? It’s a delightful blend of perfectly cooked chicken and turkey, brought together with creamy mushroom soup and cheese, layered on a breadcrumb topping. It’s like a warm hug for your taste buds! But seriously, the name might sound long-winded, but we could just call it “delicious” and be done with it. Ever pondered how such a flavorful dish came to be? Maybe it’s because, true to the saying, “the way to a man’s heart is through his stomach!”
However, this dish appeals to everyone—whether you’re a food enthusiast or just looking for an easy dinner solution. Trust me, this casserole will have your family gathering around the table in no time.
Why You’ll Love This Creamy Chicken and Turkey Slice Casserole
There are countless reasons to fall in love with Creamy Chicken and Turkey Slice Casserole. To start, it’s the ultimate main dish that brings comfort and satisfaction in every bite. The creamy texture combined with the tender chunks of meat creates a heavenly experience. You’ll be amazed at how using simple ingredients can translate into an outstanding meal.
Moreover, cooking at home is a fantastic way to save money and control what goes into your food. Why spend a fortune on dining out when you can whip up a delicious, homemade dish that your family will rave about? And let’s not forget about the crunchy breadcrumb topping that adds just the right amount of texture—think of it as a perfect counterpart to the creamy filling.
If you love the traditional chicken and rice casserole, then you’ll appreciate the delightful twist this recipe offers. So, gather the ingredients and let’s get cooking!
How to Make Creamy Chicken and Turkey Slice Casserole
Quick Overview
When you’re looking for an easy yet satisfying meal, Creamy Chicken and Turkey Slice Casserole fits the bill perfectly! This dish combines the richness of meats and cream with crispy, golden breadcrumbs, all baked to perfection. Preparation takes about 20 minutes, and then it’s simply a matter of letting the oven do the work for you!
Ingredients
- 2 cups cooked chicken, shredded
- 2 cups cooked turkey, sliced
- 1 cup cream of mushroom soup
- 1 cup sour cream
- 1 cup shredded cheddar cheese
- 1 tablespoon garlic powder
- 1 tablespoon onion powder
- Salt and pepper to taste
- 1 cup bread crumbs
- 2 tablespoons butter, melted
Step-by-Step Instructions
- Preheat the Oven: Start by preheating your oven to 350°F (175°C). This step is crucial to ensure even cooking throughout the casserole.
- Prepare the Meat: In a large mixing bowl, combine the shredded chicken and sliced turkey. This blend provides both flavor and texture to your casserole.
- Make the Creamy Mixture: To the bowl, add the cream of mushroom soup, sour cream, and half of the shredded cheddar cheese. Sprinkle in garlic powder, onion powder, salt, and pepper. Mix well until all ingredients are fully combined.
- Assemble the Casserole: Spread the meat and cream mixture evenly in a greased 9×13 inch baking dish.
- Add the Topping: In a separate bowl, combine the bread crumbs and melted butter until the crumbs are well-coated. Evenly sprinkle this mixture over the casserole.
- Final Bake: Bake in the preheated oven for 30-35 minutes, or until the casserole is bubbly and the top is golden brown.
- Serve and Enjoy: Let the casserole sit for a few minutes before serving. This allows the flavors to meld beautifully, and it’s ready to delight your family!
Top Tips for Perfecting Creamy Chicken and Turkey Slice Casserole
- Meat Substitution: While this recipe uses chicken and turkey, feel free to alternate with halal, lean meats or even plant-based proteins for a vegetarian option.
- Storage Advice: If you have leftovers, they should be stored in an airtight container in the fridge for up to 3-4 days. The casserole can be frozen for up to 2 months, just make sure to let it cool completely before freezing.
- Reheating: For the best taste and texture, reheat in the oven at 350°F (175°C) until warmed through, or use a microwave, but this may result in less crispy topping.
Storing and Reheating Tips
To preserve the flavors of Creamy Chicken and Turkey Slice Casserole, proper storage is key. Once cooled, transfer any leftovers into a sealed container and refrigerate. This will keep your casserole fresh for up to 3-4 days. If you decide to freeze it, it’s best suited for up to 2 months.
For reheating, the oven is your best friend. Preheat to 350°F (175°C) and warm the casserole until heated through, ensuring that the topping remains crispy and delicious.
Now that you know how to create this delightful Creamy Chicken and Turkey Slice Casserole, why not make it tonight? Your family will love the indulgent flavors and comforting textures, making it a dish you’ll want to prepare time and again!

Creamy Chicken and Turkey Slice Casserole
Ingredients
Meat
- 2 cups cooked chicken, shredded
- 2 cups cooked turkey, sliced
Creamy Mixture
- 1 cup cream of mushroom soup
- 1 cup sour cream
- 1 cup shredded cheddar cheese divide in half for layering
- 1 tablespoon garlic powder
- 1 tablespoon onion powder
- to taste Salt and pepper
Topping
- 1 cup bread crumbs
- 2 tablespoons butter, melted
Instructions
Preparation
- Preheat your oven to 350°F (175°C).
- In a large mixing bowl, combine the shredded chicken and sliced turkey.
- Add cream of mushroom soup, sour cream, and half of the shredded cheddar cheese to the meat blend. Sprinkle with garlic powder, onion powder, salt, and pepper. Mix until well combined.
- Spread the meat mixture evenly in a greased 9x13 inch baking dish.
- In a separate bowl, mix bread crumbs with melted butter until well-coated. Evenly sprinkle the bread crumb mixture over the casserole.
Baking
- Bake in the preheated oven for 30-35 minutes, or until bubbly and the top is golden brown.
- Let the casserole sit for a few minutes before serving.

Leave a Reply